A 49-year-old male suffered from hepatitis C complained of vertigo and hearing loss after the attack of abdominal and chest pain. During seven days his pure tone thresholds showed elevation of 10dB.
Saxizon® hydrocortizone sodium succinate was given from the dose of 300mg and was tapered every 2 days to 100mg for 6 days. However, more elevation of 10dB was recorded. Saxizon ® was discontinued without further deterioration of hearing.
Two month later, he was diagnosed as of mixed type of cryoglobulinemia, and we started the therapy with interferon (INF-α-2b).
As a result, liver function and the serum immunoglobulin level were normalized, and hearing level was greatly improved.
