生体機能の研究への磁気共鳴法の応用
1973 年 42 巻 3 号 p. 214-225
詳細
1973 年 42 巻 3 号 p. 214-225
Recent development in the application of magnetic resonance to biological systems is briefly reviewed. The magnetic resonance methods including high resolution NMR, pulse NMR and spin label EPR are described in terms of their merits and limitations in biological application. Recent interesting studies on biological macromolecules by magnetic resonance are explained in three sections : protein, nucleic acid and biological membrane. The covered topics in the protein section are histidine titration in RNase, various approaches taken for studying lysozyme, the heme-heme interaction in ;hemoglobin, oxidation-reduction in cytochrome c and few others. Paramagnetic relaxation enhancement method applied to the studies of the active sites of enzymes is also mentioned. In the nucleic acid section only tRNA studies are briefly described. The topics mentioned in the biological membrane section are molecular motions in phospholipid bilayers.
