1978 年 47 巻 12 号 p. 1096-1111
Structure and properties of synthetic polypeptides in the solid state were discussed. Various conformations of polypeptides were reviewed. A stable 7/2 distorted α-helix was presented for poly [γ-(p-chlorobenzyl L-glutamate)]. Side-chain conformations were also discussed. Allowed conformations of the side chain of poly(γ-benzyl L-glutamate) (PBLG) were searched by computer simulation. Unindexed reflections of the α-helix were discussed in conjunction with the 1.5 A reflection. Magnetic resonance including NMR and ESR was applied to study molecular motions occurring in polypeptides. Dynamic mechanical and dielectric dispersions of PBLG in the vicinity of room temperature were interpreted in terms of side-chain motions and structural characteristics of PBLG. X-ray measurements were made to obtain thermal expansion of the side-chain region and fluctuation of the α-helix. The blended mixture of PBLG and its D body was also studied.