Abstract
The purpose of this study was to clinically and microbiologically evaluate the effects of local drug delivery of Periocline® in combination with scaling and root planing (SR). This study was performed during supragingival mechanical plaque control. The four groups, i. e., I: treated only by SR, II: Periocline® applied after SR, III: Periocline® applied twice, after SR and after one week, IV: Periocline® applied four times, after SR and once a week three weeks, were assessed clinically (PD, AL, GI, BoP and SI) and microbiologically by phase contrast microscopy and anaerobic culture before and after treatment.
The results obtained were as follows:
1. Group IV showed greater improvement in PD, AL and GI than group I. The percentage of sites which bled when probed was increasingly lower in group I, II, III and IV. Sites discharging pus disappeared after treatment in all of the groups.
2. There were no significant differences among the groups in the number or percentage of motile rods or spirochetes after treatment.
3. There were no significant differences among the groups in total number of anaerobic bacteria after treatment. The number of sites in which black pigmented anaerobic rods (BPAR) were present and the number of sites in which Actinobacillus actinomycetemcomitans were present, were increasingly fewer in group I, II, III and IV. Sites containing Actinobacillus actinomycetemcomitans were no longer present after treatment in group IV.
