Abstract
Nucleotide sequence of trypsin is analysed by the DEV model for the assignment of its functional system. The number of alphabets is reduced from five (A, T, G, C, S)1) to three (A, C, S or A, G, S) or two (A, C or A, G). Results strengthen the view obtained in five-alphabet system: less-specific but exact assignment of functional system. Comparison between different numbered alphabets is made which includes electric circuit, two alphabet (0, 1) made of conductor.