2008 Volume 45 Pages 169-177
A risk evaluation framework of waterbome infectious diseases based on seroprevalence was developed and used to evaluate risk of infection by Campylobacter jejuni, Helicobacter pylori and adenoviruses in two villages in rural Cambodia. As the result, it was revealed that no outbreak of campylobacteriosis occurred in recent years.It was also revealed that almost all villagers would be infected by adenovirus in the first five years of their lives. As for H pylori infection, a high annual risk of infection (8 to 10%) was estimated and drinking water contamination with total coliform was found to be a significant risk factor (OR=5.29, 95 % C.I.=1.17 to 23.9). Although a part of villagers drank well water heavily contaminated with arsenic, the effect of arsenic on disturbing their production of serum antibody against H pylori was negligible.
