基礎心理学研究
Online ISSN : 2188-7977
Print ISSN : 0287-7651
ISSN-L : 0287-7651
特別招待講演2
記憶の物理化学的実体
井ノ口 馨
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ジャーナル フリー

2019 年 38 巻 1 号 p. 128-131

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Memories are formed through long-term changes in synaptic efficacy and are stored in the brain in specific neuronal ensembles called engram cells. However, neural mechanisms underlying memory association had been unclear. Using optogenetics and behavioral conditioning tests, we found as follows. First, an association of two different memories is caused by increasing overlapping neurons which encode both memories. Second, it is possible for us to artificially connect the link between two different memories through synchronous activation of distinct cell ensembles. Third, synapse-specific plasticity guarantees the identity and storage of individual memories. These results may give insight into therapeutic treatments for post-traumatic stress disorder.

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© 2019 日本基礎心理学会
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