A study was carried out concerning the toxicity of chemical substances, using the error root mean square method to estimate the toxicity of new chemical substances before trial production. It became possible to discriminate substances of high toxicity from substances of low toxicity by comparing the estimated distances obtained by this method, and as a result, to make the development process more efficient and reduce needless prototyping costs. The study also succeeded in obtaining design information from itemized diagnoses of the individual substances, and in finding ways to improve the parameters unique to the substances. The study showed that quality engineering enables toxicity to be estimated at an early stage in the development of chemical substances, and that quality engineering can be used to avoid chemical toxicity problems.
