Radiation Environment and Medicine
Online ISSN : 2432-163X
Print ISSN : 2423-9097
ISSN-L : 2423-9097
Report
Cytogenetic Biodosimetry in Radiation Emergency Medicine: 2. Biosafety and Chemical Safety in Biodosimetry Laboratory
Kosuke KasaiYu AbeValerie Goh Swee TingMai Tran ThanhYohei FujishimaRyo NakayamaKai TakebayashiAkifumi NakataKentaro AriyoshiHiroyuki HanadaMitsuaki A. YoshidaKatsuhiro ItoTomisato Miura
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2022 年 11 巻 1 号 p. 34-39

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In a biodosimetry laboratory, blood collected from exposed patients is cultured and the exposure dose is estimated based on the frequency of chromosome aberrations. Blood is defined as an infectious specimen because it may contain hepatitis virus and human immunodeficiency virus (HIV) and must be handled in a biosafety level (BSL) 2 facility. Due to the recent coronavirus pandemic with SARS-CoV-2, further strengthening of infection control measures is required. This article outlines the requirements for setting up a BSL2 laboratory, personal protective equipment for infection control, treatment of infectious biological waste and emergency response measures. Furthermore, it is essential to safely manage hazardous chemicals used in biodosimetry. Biodosimetry laboratories should conduct risk assessments of blood handling and chemical use and consider risk mitigation measures. In addition, laboratory personnel must educate workers on infection control and chemical safety.

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© 2022 Hirosaki University Press.
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