2015 Volume 64 Issue 6 Pages 422-426
Charged particle therapy is expected to be a novel treatment modality for hepatic tumor due to the physical properties for ideal radiation dose distribution that offers the promise of maximizing tumor control via dose escalation without excessive liver radiation exposure in patients with limited functional liver reserves. In this review, we discuss the clinical outcomes, the toxicity and implications of charged particle therapy, particularly for the treatment of hepatocellular carcinoma.