2025 Volume 74 Issue 1 Pages 87-89
The scientific evidence for the medical application of thoron, an isotope of radon, remains to be insufficient internationally. In addition, the ICRP reported that thoron progeny nuclides show higher radiobiological effects than radon progeny nuclides. For this reason, we outlined some of the research results that we have so far reported the biological effects of thoron and comparison with those of radon. As a result, we were able to suggest that, like radon ingestion, thoron ingestion enhances antioxidant function through physiological stimulation caused by the generation of trace amounts of active oxygen, thereby alleviating the symptoms of oxidative stress-related diseases. In addition, we found that thoron appears in a range with a lower optimal inhalation concentration than radon due to the difference in radioactivity characteristics, which is consistent with the ICRP report.