We examined the efficacy of a new commercial assay procedure (SCC RIABEAD®) for estimation of squamous cell carcinoma related antigen (SCC) . Intraassay and interassay variance were 4.0-14.6% and 4.6-17.0% respectively. Recovery and dilution tests gave satisfactory results. The normal range was under the level of 1.63 ng/ml. The patients with uterine cervical cancer or squamous cell carcinoma of the lung showed high positive rates. The values of SCC measured by SCC RIABEAD® were well-correlated to those by SCC RIAKIT®. However, SCC RIABEAD® showed lower values in low SCC level and higher values in high SCC level than SCC RIAKIT®.
