N-isopropyl- (123I) -p-iodoamphetamineの大脳への集積の半定量検査法: 大脳対小脳の集積比

富本 浩明; 林 理之; 河原 泰人; 清川 文秋; 福永 仁夫

doi:10.3769/radioisotopes.36.12_650

Semi-quantitative Method of N-isopropyl- (¹²³I) -p-iodoamphetamine Accumulation in Cerebrum: Cerebrum to Cerebellum Accumulation Ratio

Hiroaki TOMIMOTO, Masayuki HAYASHI, Yasuto KAWAHARA, Fumiaki KIYOKAWA, Masao FUKUNAGA

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Keywords: N-isopropyl- (iodine-123) -p-iodoamphetamine, cerebrum, cerebellum, accumulation ratio, blood flow, vascular disorder, single photon emission computed tomography

JOURNAL FREE ACCESS

1987 Volume 36 Issue 12 Pages 650-652

DOI https://doi.org/10.3769/radioisotopes.36.12_650

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Abstract

Semi-quantitative method of IV isopropyl- (¹²³I) -p-iodoamphetamine (¹²³I-IMP) accumulation in cerebrum by using ¹²³I-IMP SPECT was tried. Ratio of counts in whole cerebrum to those in normal cerebellum was calculated, and this accumulation is defined as cerebrum to cerebellum accumulation ratio. In group of patients with dementia or patients who were remaining in bed, significantly low accumulation ratio was observed, while in “normal” group, no differences in sex and aging were observed. Calculations of cerebrum to cerebellum accumulation ratio was concluded as a useful method of evaluating the accumulation of ¹²³I-IMP in cerebrum.

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