15O標識ガス剤吸入によるPET検査の臨床的有用性の評価

吉川 京燦; 岡田 淳一; 宇野 公一; 有水 昇; 八木下 敏志行; 木内 一郎; 岡 信男; 岡住 慎一; 加賀谷 秋彦; 岩崎 康; 間賀田 泰寛; 小西 淳二; 米倉 義晴

doi:10.3769/radioisotopes.40.11_444

A Clinical Trial on Evaluation of Usefulness of ¹⁵O Labeled Gas Postitron Emission Tomography

Kyosan YOSHIKAWA, Junichi OKADA, Kimiichi UNO, Noboru ARIMIZU, Toshiyuki YAGISHITA, Ichirou KIUCHI, Nobuo OKA, Shinichi OKAZUMI, Akihiko KAGAYA, Yasushi IWASAKI, Yasuhiro MAGATA, Junji KONISHI, Yoshiharu YONEKURA

Author information

Kyosan YOSHIKAWA
Department of Radiology Chiba University School of Medicine
Junichi OKADA
[in Japanese]
Kimiichi UNO
[in Japanese]
Noboru ARIMIZU
[in Japanese]
Toshiyuki YAGISHITA
Department of Neurology Chiba Unibersity School of Medicine
Ichirou KIUCHI
Department of Neurosurgery Chiba Unibersity School of Medicine
Nobuo OKA
Department of Neurosurgery Chiba Unibersity School of Medicine
Shinichi OKAZUMI
Second Department of Surgery Chiba Unibersity School of Nuclear Medicine
Akihiko KAGAYA
Third Department of Internal Medicine, Chiba Unibersity School of Medicine
Yasushi IWASAKI
Department of Nuclear Medicine Kyoto University School of Medicine
Yasuhiro MAGATA
Department of Nuclear Medicine Kyoto University School of Medicine
Junji KONISHI
Department of Nuclear Medicine Kyoto University School of Medicine
Yoshiharu YONEKURA
Department of Brain Pathophysiology, Kyoto University School of Medicine

Keywords: oxygen-15 labeled gas, positron emission tomography, cerebrovascular disease, tumor, cardiac disease, regional tissue metabolism

JOURNAL FREE ACCESS

1991 Volume 40 Issue 11 Pages 444-451

DOI https://doi.org/10.3769/radioisotopes.40.11_444

Details

Abstract

Positron emission tomographic study (PET study) using ¹⁵O labeled gases was carried out in 108 patients with cerebrovascular diseases, tumor, cardiac diseases and others to evaluate the clinical usefulness of ¹⁵O labeled gas PET study.
The side-effect of ¹⁵O labeled gas was not odserbed in any cases, and ¹⁵O labeled gas PET study was judged to be highly safe technique.
Quantitative information with ¹⁵O labeled gas PET study was judged to be useful clinically in 94-96% of the cases. In comparison with other radionuclide images, X-ray CT and MRI, the information with ¹⁵O labeled gas PET study was tended to be superior or more useful to that with other imaging technique in 81% of cases.
¹⁵O labeled gas PET study was judged to be useful in 99% of the cases. It is concluded that ¹⁵O labeled gas PET study is a useful technique for quantitative measurement of regional tissue metabolism.

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