In order to investigate the clinical usefulness of positron emission tomography (PET) studies using the inhalation of oxygen-15 labeled gas, clinical trial was performed. PET studies were carried out using 15O labeled gas produced by automated 15O gas production system (ARIS G1) in 72 patients with various neurological disorders. In all cases, the labeled gas was produced in a stable condition by ARIS G1 and no adverse reaction was observed. Overall assessment for the clinical usefulness of PET study using ARIS G1 was determined as follows: 50% as highly useful, 41.7% as useful and 8.3% as fairly useful.
In conclusion, PET studies using 15O gas production system were useful in patients with various brain diseases.
