Positron Emission Tomographyによる大腿骨頭部血流量・血液量の計測の試み ― [C15O2] 二酸化炭素, [C15O] 一酸化炭素による検討―

山下 正人; 稲葉 正; 久保 俊一; 井手 真理子; 牛嶋 陽; 古谷 誠一; 小田 洋平; 水川 典彦; 中橋 彌光

doi:10.3769/radioisotopes.40.2_75

Measurement of Blood Flow and Blood Volume of the Femoral Head by Positron Emission Tomography (PET) Using C¹⁵O₂ and C¹⁵O

Masato YAMASHITA, Tadashi INABA, Shunichi KUBO, Mariko IDE, Yo USHIJIMA, Seiichi FURUYA, Yohei ODA, Norihiko MIZUKAWA, Hisamitsu NAKAHASHI

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Keywords: positron emission tomography, femoral bone, blood flow, blood volume, oxygen-15 carbon dioxide, oxygen-15 carbon monoxide

JOURNAL FREE ACCESS

1991 Volume 40 Issue 2 Pages 75-78

DOI https://doi.org/10.3769/radioisotopes.40.2_75

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Abstract

A preliminary study was carried out to evaluate whether the blood flow (F) of the femoral head can be measured by PET on the subjects (6 males, aged 54-84, mean 69.3 years) with prostate disorders (no bone lesions) . For the F study, C¹⁵O₂ was inhaled in a single breath with dynamic scan for 5 minutes. The blood volume (V) was determined by the C¹⁵O study. The F (mean±1 s.d.) was 14.0±7.8 ml/100 ml [tissue] /min, the partition coefficient was 0.112±0.054, and the V was 2.23±0.56 ml/100 ml.

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