Serum PSA level in patients with urogenital disorders was measured by PSA kits using monoclonal antibody. Serum PSA values in 122 healthy men were 1.1 ± 0.3 ng/ml (mean ± S.D. ) and upper limit of mean+2 S.D. in healthy men was 1.7 ng/ml. Serum PSA levels in 15 male patients with prostate cancer were more increased than those in 11 male patients with prostate hypertrophy (556.9±896.1 ng/ml vs. 8.4±10.4 ng/ml, p<0.001) . It is our conclusion that the estimate of serum PSA level provided a useful diagnostic information of prostate cancer.
