1994 Volume 43 Issue 8 Pages 457-461
123I-IMP clearance on dynamic lung scintigraphy was studied by two exponential compartments analysis in order to evaluate the effects of aging and smoking on the pulmonary function. Twenty-four patients (14 smokers and 10 non-smokers), referred for 123I-IMP brain perfusion study underwent lung dynamic scintigraphy for 42 min immediately after 123I-IMP injection. In the non-smoking group 123I-IMP lung clearance was delayed with aging. A significant correlation was found between aging and clearance rate in the lung. There was also a significant difference between the clearance rates between smoker and non-smoker group. These findings suggest that smoking and aging affect the pulmonary function.
