酸素15水注射液合成装置を用いたPET検査の臨床的有用性

米倉 義晴; 石田 良雄; 間賀田 泰寛; 三宅 義徳; 林田 孝平; 石津 浩一; 岡沢 秀彦; 工藤 崇; 東 達也; 玉木 長良; 笠木 寛治; 小西 淳二

doi:10.3769/radioisotopes.45.11_689

Clinical Value of Positron Emission Tomography (PET) Using Automated Production System of Oxygen-15 Water

Yoshiharu YONEKURA, Yoshio ISHIDA, Yasuhiro MAGATA, Yoshinori MIYAKE, Kohei HAYASHIDA, Koichi ISHIZU, Hidehiko OKAZAWA, Takashi KUDO, Tatsuya HIGASHI, Nagara TAMAKI, Kanji KASAGI, Junji KONISHI

Author information

Yoshiharu YONEKURA
Biomedical Imaging Research Center, Fukui Medical School
Yoshio ISHIDA
National Cardiovascular Center
Yasuhiro MAGATA
Kyoto University Hospital
Yoshinori MIYAKE
National Cardiovascular Center
Kohei HAYASHIDA
National Cardiovascular Center
Koichi ISHIZU
Kyoto University Hospital
Hidehiko OKAZAWA
Kyoto University Hospital
Takashi KUDO
Kyoto University Hospital
Tatsuya HIGASHI
Kyoto University Hospital
Nagara TAMAKI
Kyoto University Hospital
Kanji KASAGI
Kyoto University Hospital
Junji KONISHI
Kyoto University Hospital

Keywords: positron emission tomography (PET), oxygen-15, water, clinical trial, blood flow, brain, heart, tumor, labeling

JOURNAL FREE ACCESS

1996 Volume 45 Issue 11 Pages 689-695

DOI https://doi.org/10.3769/radioisotopes.45.11_689

Details

Abstract

We examined the safety and the clinical usefulness of oxygen-15 water produced by the automated synthesis system (Sumitomo Heavy Industries, type 01) by means of positron emission tomography (PET) . This clinical trial involved 60 patients with various diseases. No side effects were observed by subjective and objective symptoms, physical findings, and laboratory tests. In all 60 cases, the PET images of good quality were obtained. In 95% of the cases, PET provided equivalent or better clinical information compared with other clinical examinations. The overall assessment of the clinical usefulness demonstrated that the method was useful or extremely useful in 59 cases (98%) .

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