γ線4Gyまたは10Gy照射マウスの血液中における⁵⁹Feの存在状態

抄録

In a previous paper, we studied elimination and presence rates of nuclides injected in irradiated mice to investigate metabolic mechanism of several essential metals in injured mice leading to recovery after sublethal irradiation, and it was observed that the elimination and the presence rates of elements in tissues and organs showed a difference between the doses, particularly for ⁵⁹Fe in liver and blood of mice. In this paper, further observations with biochemical states of ⁵⁹Fe in the blood of irradiated mice are described as well as with distribution of ⁵⁹Fe in the blood. An accumulation of ⁵⁹Fe to erythrocytes was remarkably decreased by the irradiation, and a big radioactive peak (P-1) was seen in a profile of gel filtration of hemolysates in both unirradiation (control) and irradiation samples 2 days after the irradiation. At 8 days after the irradiation, the presence rate of ⁵⁹Fe in the erythrocytes increased, and in the profile of gel filtration, for 10 Gy irradiation, the peak P-1 decreased and another radioactive peak was observed, but the difference between 4 Gy and control was not clear. These results suggested a metabolic process leading individuals to recovery from injury after irradiation.