99mTc-GSAシンチグラフィによる肝機能評価の有用性 ―新指標の開発―

宮本 浩仁; 長町 茂樹; 陣之内 正史; Leo G. FLORES II; 中原 浩; 大西 隆; 二見 繁美; 田村 正三; 渡辺 克司

doi:10.3769/radioisotopes.47.120

Usefulness of ^99mTc-GSA Scintigraphy for Evaluation of Hepatic Function

—Development of New Index—

Hirohito MIYAMOTO, Shigeki NAGAMACHI, Seishi JINNOUCHI, Leo G. FLORES II, Hiroshi NAKAHARA, Takashi OHNISHI, Shigemi FUTAMI, Shozo TAMURA, Katsushi WATANABE

Author information

Hirohito MIYAMOTO
Department of Radiology, Miyazaki Medical College
Shigeki NAGAMACHI
Department of Radiology, Miyazaki Medical College
Seishi JINNOUCHI
Department of Radiology, Miyazaki Medical College
Leo G. FLORES II
Department of Radiology, Miyazaki Medical College
Hiroshi NAKAHARA
Department of Radiology, Miyazaki Medical College
Takashi OHNISHI
Department of Radiology, Miyazaki Medical College
Shigemi FUTAMI
Department of Radiology, Miyazaki Medical College
Shozo TAMURA
Department of Radiology, Miyazaki Medical College
Katsushi WATANABE
Department of Radiology, Miyazaki Medical College

Keywords: technetium-99m-galactosyl serum albumin (^99mTc-GSA), hepatic functional imaging obstructive jaundice, reserved hepatic function

JOURNAL FREE ACCESS

1998 Volume 47 Issue 2 Pages 120-128

DOI https://doi.org/10.3769/radioisotopes.47.120

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Abstract

^99mTc-GSA scintigraphy was performed to evaluate reserved hepatic function in 32 patients with hepatobiliary tumor. Each parameters; HH15, LHL15 and T_1/2 showed good correlation with ICG15 in patients without obstructive jaundice.
Contrary, each indices did not significantly correlate with ICG15 in cases including obstructive jaundice. Each indices obtained from ^99mTc-GSA scintigraphy was useful parameters to reflect liver functional reserve which was not affected by hyperbilirubinemia.
New index, T_1/2 was more useful than other indices for differentiating hepatic dysfunctional state from normal condition.

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