Abstract
Prognosis and prognostic factors in 58 patients with malignant lymphoma of the thyroid gland were analyzed. From 1975 to 1987, 58 patients with non-Hodgkin's lymphoma originating in the thyroid gland were treated at Ito Hospital. Their ages at the time of the initial diagnosis ranged from 36 to 81 years (mean 64.2 years). Twelve of them were male and forty-six female, giving a female-to-male ratio of 3.8. In this study the overall 5 or 10-year survival rate was 61.2% each. The 5-year survival rate in stage IV disease (16.9%) was significantly smaller than that in stage Is (85.7%). By the LSG classification, both the 5 and 10-year survival rates in diffuse lymphomas (50.3% each) were significantly smaller than those in follicular lymphomas (100% each). By the Working Formulation, both the rates in intermediate grade (53.8% each) and high grade (35.3% each) were significantly smaller than that in low grade (100% each). The 5 and 10-year survival rates in patients of 60 years and over (55.5% each) were significantly smaller than those of less than 59-years (84.8% each). Sexual difference offered no apparent correlation to survival. Cell types of non-Hodgkin's lymphomas of the thyroid gland appear to be significant determinants of prognosis of the patients.
