Cushing's syndrome due to primary adrenocortical nodular dysplasia (hereinafter referred to as PAND) as reported by Meador is thought to be adrenooriginated hyperfunction presenting multiple nodules in the corticis of bilateral adrenals 1).Bilateral adrenalectomy is performed for its treatment and postoperative steroid supplement is necessary for life. Its prognosis is comparatively good, but very few cases of postoperative delivery have been reported in spite of its juvenile predominance. The present case is a woman who received total adrenalectomy for Cushing's syndrome at the age of 11, and subsequently succeeded in planned pregnacy-delivery.
First, our department defined postoperative cortisol supplement as 20mg/day, but during pregnancy the same dose was kept, juding from her course of pregnancy and the results of various hormone tests. Normal delivery occurred at the 40th week of pregnancy and postpartum course was eventless. Now, the child presents no anomaly, but good postnatal development. Thus, at the present state of advanced medical control and in the absence of other complications, pregnancy-delivery is though possible even after adrenalectomy.