We experienced two cases of corrosive esophagitis caused by an acid or alkali chemical substance taken during a suicide attemt one case of acid-caused corrosive esophagitis had gastrostomy just after the injury and had been receiving bougienage for four years. However, because of dysphagia, a subtotal-esophagectomy and intra-thoracic esophagogastrectomy were performed. Its specimen had no ulcer and scar, but Barrett epithelium was found which lengthened by 25 mm to oral-side from the E-C junction without malignancy. The second case of alkali-caused corrosive esophagitis had subtotal-esophagectomy and retro-sternal esophagecotmy four months later after the injury, where the esophagus firmly adhered to the surrounding tissues. Its specimen had deep ulcers. After operations, both two cases have been able to eat normal meals.
Barrett esophagus might be formed following by the regeneration of columnar epithelium.