Abstract
Perianal Paget's disease has some unique aspects different from other malignant tumors in that it often associates with a malignant tumor and has a wide range of dermal infiltlation. These facts demand careful attentions in the treatment of the disease. We encountered a 68-year-old male patient with the disease associated with rectal cancer. In the preoperative mapping of biopsy, the anal lesion to be resected was determined and excision of rectum was carried out under consideration of postoperative better maintenanse of defecation function and surgical radicality. Moreover, a wide range of defected skin around the anal could be repaired with pediculated flap by one-step approach. As far as we could review, only 15 cases (indluding this) of perinal Paget's disease associated with rectal cancer have been reported in Japan. We present here several attentions for appropriate resection of this relatively rare disease.