Abstract
New human cell lines from 4 patients were established. One derived from normal female, 2 from patients with chronic granulocytic leukemia whose bone marrow cells had Philadelphia chromosome, and one from a patient with XY/XXY mosaic of Klinefelter syndrome.
Chromosome constitutions of these cell lines were 46, XX in normal and chronic granulocytic leukemia and 47, XXY in mosaic of Klinefelter syndrome.
Morphological and functional characteristics of cell lines were discussed and usefullness of cell lines in hematological study was stressed.
