臨床血液
Online ISSN : 1882-0824
Print ISSN : 0485-1439
ISSN-L : 0485-1439
短報
単球・好酸球増加を欠き,再発時にbiphenotypicな芽球が出現したinv (16)白血病(M2)の1例
河野 秀久源 陽子羽藤 高明安川 正貴宮本 直明栗原 憲二近藤 俊文
著者情報
ジャーナル 認証あり

1992 年 33 巻 9 号 p. 1287-1289

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抄録

Inversion of chromosome 16 was found in a 73-year-old female with acute myeloblastic leukemia (FAB:M2). Complete remission was achieved by combined chemotherapy (DNR, Ara-C, 6-MP, Prednisolone), but she relapsed 6 months later without CNS involvement and died of respiratory failure presumably due to cerebrovascular accident during remission reinduction chemotherapy. Biphenotypic surface markers (CD2+ and CD13+) were observed on relapse. Eosinophilia was not observed throughout. Our patient and the other reported case suggest that biphenotypism and the lack of eosinophilia and monocytosis in inv (16) leukemia may be correlated with a poor prognosis.

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© 1992 一般社団法人 日本血液学会
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