Rinsho Ketsueki
Online ISSN : 1882-0824
Print ISSN : 0485-1439
ISSN-L : 0485-1439
Donor cell-derived acute myeloid leukemia developed shortly after allogeneic bone marrow transplantation for MDS overt leukemia
Ryoichi TAKAHASHI, Chihiro SHIMAZAKI, Tohru INABA, Masao NAKAGAWA, Masanobu YAMAOKA
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Keywords: Bone marrow transplantation, Recurrence, Donor cell leukemia
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2002 Volume 43 Issue 10 Pages 963-965

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Abstract
We report a patient with myelodysplastic syndrome (MDS) overt leukemia who developed an acute myeloid leukemia (AML) in donor cells shortly after bone marrow transplantation (BMT) from his HLA-matched sibling. Molecular analysis using microsatellite repeats by polymerase chain reaction proved the new leukemia to be of donor cell origin. The patient received chemotherapy with idarubicin and ara-C, but he died due to mucormycosis.
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© 2002 The Japanese Society of Hematology
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