短報
白血化皮膚原発未分化大細胞リンパ腫に対するbrentuximab vedotin長期投与
キーワード:
CD30,
Brentuximab vedotin,
Primary cutaneous anaplastic large cell lymphoma,
Leukemic presentation
2018 年 59 巻 2 号 p. 187-190
詳細
2018 年 59 巻 2 号 p. 187-190
We report a case of long-term administration of brentuximab vedotin (BV) for primary cutaneous anaplastic large cell lymphoma (pc-ALCL) with leukemic change. A 67-year-old man with lymphadenopathy was admitted to our hospital. Six years ago, he was diagnosed with pc-ALCL at another hospital, and complete remission was achieved with radiation therapy. We performed a biopsy of his lymph node and diagnosed the recurrence of pc-ALCL with leukemic change. Initially, CHOP and GCD regimens were ineffective; however, partial remission was achieved following BV therapy. Thus far, he has received 42 courses of BV; he has responded well to the treatment and no serious side effects have been observed.
