Glycophorin Aの発現を認めたB細胞性急性リンパ芽球性白血病

松本 洋典; 杉谷 未央; 西川 理菜; 長田 浩明; 岩本 伸紀; 栗山 幸大; 大城 宗生; 平川 佳子; 岩井 俊樹; 稲葉 亨; 内山 人二

doi:10.11406/rinketsu.62.717

Case Reports

B-cell acute lymphoblastic leukemia with glycophorin A expression

Yosuke MATSUMOTO, Mio SUGITANI, Rina NISHIKAWA, Hiroaki NAGATA, Nobuki IWAMOTO, Kodai KURIYAMA, Muneo OHSHIRO, Yoshiko HIRAKAWA, Toshiki IWAI, Tohru INABA, Hitoji UCHIYAMA

Author information

Yosuke MATSUMOTO
Department of Hematology, Japanese Red Cross Kyoto Daiichi Hospital
Mio SUGITANI
Department of Hematology, Japanese Red Cross Kyoto Daiichi Hospital
Rina NISHIKAWA
Department of Hematology, Japanese Red Cross Kyoto Daiichi Hospital
Hiroaki NAGATA
Department of Hematology, Japanese Red Cross Kyoto Daiichi Hospital
Nobuki IWAMOTO
Department of Hematology, Japanese Red Cross Kyoto Daiichi Hospital
Kodai KURIYAMA
Department of Hematology, Japanese Red Cross Kyoto Daiichi Hospital
Muneo OHSHIRO
Department of Hematology, Japanese Red Cross Kyoto Daiichi Hospital
Yoshiko HIRAKAWA
Department of Hematology, Japanese Red Cross Kyoto Daiichi Hospital
Toshiki IWAI
Department of Hematology, Japanese Red Cross Kyoto Daiichi Hospital
Tohru INABA
Faculty of Clinical Laboratory, Kyoto Prefectural University of Medicine
Hitoji UCHIYAMA
Department of Hematology, Japanese Red Cross Kyoto Daiichi Hospital

Keywords: Erythroid, Lymphoid, Glycophorin A, Mixed phenotype acute leukemia

JOURNAL RESTRICTED ACCESS

2021 Volume 62 Issue 7 Pages 717-720

DOI https://doi.org/10.11406/rinketsu.62.717

Details

Abstract

This study reports a case of a 49-year-old woman having B-cell acute lymphoblastic leukemia with glycophorin A, a representative erythroid marker, expression. According to the WHO criteria for mixed phenotype acute leukemia (MPAL), erythroid lineage is not defined, and to the best of our knowledge, only one other case with erythroid/B-cell biphenotypic acute leukemia has been reported previously. To establish the disease entity and clarify the pathophysiology of erythroid/lymphoid MPAL, additional cases need to be analyzed.

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