Species Assignment of Pathogenic Nocardia by Simple and Rapid Drug Sensitivity Test (in Japanese with English abstract)

Abstract

Pathogenic Nocardia species was found to have characteristic drug susceptibility profiles against certain ranges of chemotherapeutic agents, such as imipenem, aminoglycosides and 5-fluorouracil (5-FU). Based on the individual susceptibility patterns (expressed as + for sensitive and - for nonsensitive) to 50 μg/ml of imipenem, tobramycin and 5-FU, clinical isolates of Nocardia are easily and rapidly assignable to N. brasiliensis (−,+,−), N. asteroides (+,+,−), N. farcinica (+,−,−) and N. nova (+,−,+).