AXIMA-TOF^{2 TM} ―新規MALDI TOF/RTOF 質量分析計による生体高分子分析

抄録

With the development of proteomics, biological researchers are increasingly using mass spectrometer. Hence, it is required for the analytical instruments to analyze the many kinds of biomolecules immediately and easily. The AXIMA-TOF^{2 TM}, a MALDI TOF-TOF system features a novel, dual ion gate capable of high resolution precursor ion selection and high energy CID cell. This instrument has a superior ability of protein identification. In addition, it can be applied to the study of different classes of biomolecules. The following three features show that AXIMA-TOF^{2 TM} can contribute to the analysis of biomolecules.
1) The unique curved field reflectron enables the acquisition of all PSD and CID fragment ion without stepping the reflectron voltage.
2) High energy CID-MS/MS can generate and detect a large amount of valuable product ions to get structural information.
3) The high performance monoPULSE ion gate can select target ion correctly from crowded MS spectra of complex samples such as mixtures and be able to measure MS/MS spectra.