The formation of split ends is one of the most important problems especially for women to present a good appearance. For the primary split ends care, the mechanical recovery of damaged hair fibers is of special importance since hair does not self-recover. In this work, the effects of cosmetic treatments on the generation of split ends have been investigated by auto-brushing machine as an accelerative method which is closer to the actual hair care process. These results strongly suggested that the important factor of the split ends formation was due to the structural changes of amorphous matrix proteins of hair fibers. We found that a diethylene glycol monoethylether (Ethyl Carbitol; EC) treatment was the most effective of all treatments we tested in inhibiting the split ends generation of permed hair, and EC treated permed hair behaved almost identically with untreated normal hair as far as the percentage of split ends generation was concerned.