2002 年 30 巻 1 号 p. 23-27
The prospective effect of bypass surgery against recurrent bleedings should be statistically evaluated to establish treatment guidelines for moyamoya disease with hemorrhagic onset. Twelve Japanese centers have combined to evaluate the benefits of direct anastomotic bypass surgery in randomized patients who have experienced hemorrhagic episodes related to moyamoya disease and who have received either best medical treatment alone or best medical treatment plus extracranial-intracranial bypass surgery. This prospective study (Japan Adult moyamoya ‹JAM› Trial) was initiated in January 2001.