抄録
New liquid embolization method using estrongen-alcohol and polyvinyl acetate was utilized in brain AVM's. Estrongen dissolved in 25% ethanol (estrogen-alcohol) causes diffuse capillary to arteriole obliteration, while ethanol soluble polymer, polyvinyl acetate containing material (PVac solution) causes larger vessel occlusion without resultant catheter gluing, unwanted tissue reactions. Thirty six cases of surgically inaccessible or difficult AVM's were embolized by the infusion of estrogen-alcohol followed by PVac solution in 73 sessions. Angiographical cure was achieved in 3 cases, more than 90% obliteration in 16 cases without any difficulties related to embolic materials. Successful surgical resection was carried out in 8 cases. Adjunct radiation therapy was used in 9 cases which lead to progressive diminution of nidus. This newly developed method may be more effective and safer than the conventional one to treat the inoperable brain AVM's and to make surgical excision or radiosurgical therapy suitable in surgically difficult AVM's.
