末梢神経伝導速度に及ぼす鉛の影響に関する労働衛生学的研究
(I) 鉛作業者における観察
1993 年 37 巻 2 号 p. 79-83
詳細
1993 年 37 巻 2 号 p. 79-83
Lead exposure indices and peripheral nerve conduction velocities were measured in 15 male workers (age: 46.7±9.9 years) exposed to lead at a secondary lead refinery. The results were as follows: 45.0±15.9μg/100g lead in blood, 206±114μg/l lead in urine, 230±322μg/l coproporphyrin in urine, 21.2±21.6mg/l δ-aminolevulinic acid, 12.9±1.1g/dl hemoglobin and a hematocrit of 42.8±2.7%. These results indicated a medium level of exposure to lead for the workers examined. Negative correlations were found between lead in blood and motor (MCV) and sensory (SCV) peripheral nerve conduction. Higher correlations were found in particular between lead in blood and MCV of the left peritoneal nerve (r=-0.51), SCV of the right median nerve (r=-0.62) and the right ulnar nerve (r=-0.59). The correlation between lead in blood and SCV seemed to be higher than that between lead in blood and MCV.
