側頭葉前部切除術が意味ネットワークに及ぼす影響

多次元尺度構成法を用いて

抄録

This study examined the effects of anterior temporal lobectomy on semantic network. 22 patients who underwent left (LATL, n = 11) or right (RATL, n = 11) anterior temporal lobectomy were administered test of verbal fluency test, preoperatively and 3 weeks, 1 year postoperatively. The semantic network was derived by multidimensional scaling analysis based on data from the animal category fluency test. In the preoperative period LATL group showed the breakdown of semantic network, but the semantic network was conceptually organized in the postoperative period. The results indicated the reduction of seizure frequency improved the semantic network of LATL. On the other hand, RATL group showed persistent breakdown of semantic network after surgery. This suggested that the right anterior temporal lobe might be involved in semantic network.