Preparation of PLGA Microcapsules with Use of W/O Emulsion Droplets

Abstract

Microcapsules have attracted much attention as a drug career. In the current study, we have prepared biodegradable poly (lactide-co-glycolide) (PLGA) microcapsules via the deposition of PLGA on W/O emulsion droplets. A combination of scanning electron microscopy (SEM) and confocal laser scanning microscopy (CLSM) demonstrates the formation of PLGA microcapsules with a diameter of 5∼10 μm. The formation mechanism of PLGA microcapsules is proposed on the basis of the experimental results.