Journal of the Japan Society of Colour Material
Online ISSN : 1883-2199
Print ISSN : 0010-180X
ISSN-L : 0010-180X
Original Research Paper
Preparation of PLGA Microcapsules with Use of W/O Emulsion Droplets
Hiroshi FUKUSHIMAMasachika HASHINOKenichi SAKAIHideki SAKAITamotsu KONDOMasahiko ABE
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2009 Volume 82 Issue 12 Pages 545-548

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Abstract

Microcapsules have attracted much attention as a drug career. In the current study, we have prepared biodegradable poly (lactide-co-glycolide) (PLGA) microcapsules via the deposition of PLGA on W/O emulsion droplets. A combination of scanning electron microscopy (SEM) and confocal laser scanning microscopy (CLSM) demonstrates the formation of PLGA microcapsules with a diameter of 5∼10 μm. The formation mechanism of PLGA microcapsules is proposed on the basis of the experimental results.

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© 2009 Japan Society of Colour Material
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