An infant with a giant cystic lymphangioma of the neck underwent tracheotomy and conservative resections after repetitive intracystic injections of OK-432. Surgery dramatically improved both respiration and swallowing, and OK-432 injections were effective as preliminary chemotherapy. Vocalization was partly impaired by the use of a tracheostomy cannula. However, this had little effect on speech development, which enabled common communication at a primary school from the age of six to ten. The course of upper airway management was good, but unfortunately, the patient died of streptococcal toxic shock syndrome (STSS) caused by group A streptococcal infection at the age of eleven.
