皮膚悪性リンパ腫・最近10年間の進歩

抄録

The studies on cutaneous malignant lymphoma have made great progress during the last twenty years, especially the last ten years.
In this paper, we reviewed the historical overview on the concept of cutaneous malignant lymphoma, especially (1) cutaneous T-cell lymphoma (CTCL) and cutaneous B-cell lymphoma (CBCL), (2) on the pathogenesis of CTCL and CBCL, (3) on the histopathological classification of non-Hdgkin's lymphoma, (4) on the clinical staging classification of primary CTCL and CBCL, (5) on the relationship between CTCL and adult T-cell leukemia/lymphoma (ATL), (6) on the molecular biology for diagnosis of CTCL and CBCL, (7) on the mechanism of the onset of primary CTCL and CBCL, (8) on the treatment and management of primary CTCL and CBCL and (9) on the future of the research for primary CTCL and CBCL.