We reported two cases of angiosarcoma of the scalp (case 1: 71 years-old male, case 2: 68 years-old female) . Both patients showed recurrence of the skin after chemotherapy (carboplatin, ifosfamide, vindecine), and IL-2 therapy. Therefore we perfomed intravenous chemotherapy of docetaxel (40mg/body, once a week), that resulted in complete remission of the skin lesion (Case 1) and partial remission of cervical lymphnode (Case 2).
In our cases, docetaxel was administrated in multi-therapy resistant patient, and it was effective. We suggest that docetaxel would be helpful for angiosarcoma of the scalp that resisted for the other therapy.[Skin Cancer (Japan) 2001; 16: 99-103]