Skin Cancer
Online ISSN : 1884-3549
Print ISSN : 0915-3535
ISSN-L : 0915-3535
線維肉腫に近い組織像の共存が認められた大型の隆起性皮膚線維肉腫の1例
松岡 由恵杉村 知江子勝浦 純子沼原 利彦窪田 泰夫石川 雅士羽場 礼次小林 省二
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2002 年 17 巻 3 号 p. 246-250

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For about a two-year duration, a patient (a 44-year-old male), had an 8×8×6cm, dome-shaped, elastic hard subcutaneous tumor on his central abdomen, close to his navel, which showed no adherence to the underlying muscles in a CT scan examination. We first performed a skin biopsy, and diagnosed DFSP. We then excised the whole tumor, and further fascia was additionally excised with a 2cm surgical margin. A histologic evaluation showed that the first biopsied tumor sample consisted of ordinary dermatofibrosarcoma protuberans (DFSP) composed of uniform spindle-shaped tumor cells in storiform patterns. The second sample, however, appeared to be compatible with fibrosarcoma in some areas, because it contained a dense proliferation of atypical spindle cells arranged in fascicular and herring-bone patterns. While immunohistochemical staining for CD34 was positive in the DFSP area, it was negative in the fibrosarcomatous area. No recurrence or metastasis was seen during the follow-up period of seven months. Furthermore, in this study we have reviewed and summarized the literature of ‘fibrosarcomatous variant of dermatofibrosarcoma protuberans’ in Japan. [Skin Cancer (Japan) 2002; 17: 246-250]
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© 日本皮膚悪性腫瘍学会
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