Abstract
From surveillance by Wakayama Dermatologic Association between 2005 and 2011, (1) hand-foot-mouth disease was found to be most prevalent in Wakayama prefecture in 2011 within this period. In addition, in 2011, (2) we had many cases with remarkable skin lesions and/or subsequent nail change. (3) The proportion of patients aged 20 and over was higher in 2011 than in other years. By weekly reports from the National Institute of Infectious Disease of Japan, hand-foot-mouth disease was shown to be most prevalent in 2011 within the period between 2002 and 2011, and Coxsackievirus A6 was most frequently detected in this epidemic. There are papers about cases of hand-foot-mouth disease by Coxsackievirus A6 with remarkable skin lesions or subsequent nail lesions. It is suggested that many adults were infected with Coxsackievirus A6 and this may be one of the reasons for the hand-foot-mouth disease epidemic in 2011.Skin Research, 12: 12-17, 2013
