催涙ガスCN (ω-クロロアセトフェノン) による皮膚炎

抄録

1-Chloroacetophenone, active ingradient in a tear-gas, CN, widely used by police authorities in Japan, was found to produce allergic contact dermatitis in exposed demonstrators in high incidence. Of 48 students in a barricade, shot with 1-chloroacetophenone, 37 suffered from acute contact dermatitis varing from erythema to severe bulla. In 15 cases, spontaneous flare-up phenomenon was observed 7 to 14 days after exposure. The results of patch test examinations in man and guinea pigs indicated that 1-chloroacetophenone is a potent sensitizer and a strong primary irritant.