2011 Volume 26 Issue 4 Pages 563-568
A 34-year-old man visited a hospital because of the abdominal pain. Abdominal ultrasonography and abdominal CT showed multiple liver tumors and a mass, 4cm in diameter, at the uncus of the pancreas. Probe laparotomy was performed at the hospital. Intraoperative diagnosis was pancreatic tumor and multiple liver metastases. Intraoperative biopsy of the liver tumor was diagnosed histologically as well-differentiated neuroendocrine carcinoma. After discharge from the hospital, he was admitted to our hospital. Serum levels of insulin, gastrin and glucagon were within normal range. Non-functional pancreatic neuroendocrine carcinoma with multiple liver metastases was diagnosed. Chemotherapy with etoposide (ETP) and cisplatin (CDDP) was commenced. Chemotherapy induced stable disease and then pyrolus-preserving pancreatoduodenectomy (PPPD) with partial colectomy and partial resection of the liver was performed. Histological diagnosis was well differentiated neuroendocrine carcinoma. He has been well for 14 months since the operation although recurrence has been observed in the liver.
