Abstract
We report an autopsy case of a 62-year-old man who died of massive gastric bleeding due to a giant gastric submucosal tumor (SMT) with multiple liver metastases. Histologically this SMT was composed of extremely pleomorphic cells that showed no differentiation towards any cell type. Hematoxylin-eosin (HE) staining as well as immunohistochemical analysis indicated that this pleomorphic sarcoma was a malignant fibrous histiocytoma ( MFH) . Another characteristic of this gastric SMT was that more than 90% of the tumor was necrotic and hemorrhagic. Vascular proliferation was obvious and a structure similar to hemangiopericytoma was recognized in the metastatic lesions of liver. This patient died within one month of presentation of symptoms.
