32 Androcymbine型化合物およびMorphinandienoneの合成
詳細
Recently, several morphinandienone- and androcymbine-type alkaloids were isolated, but the general approach to these alkaloids has not yet been investigated. Therefore, we are currently investigating the syntheses of morphinandienone and androcymbine-type compounds, and we wish to report the syntheses of O-methylflavinanthine (XIX), amurine (VIII) and demethoxy-O-methylandrocymbine (XIV) by the application of Pschorr reaction. It is noteworthy that this modified Pschorr reaction supplies the useful and important ways for the syntheses of many isoquinoline alkaloids, such as proaporphine, homoproaporphine, erythrina, protostephanine and Amaryllidaceae alkaloids.
