23 Capsicum属植物の新鎖状ジテルペン配糖体(口頭発表の部)

抄録

Novel acyclic diterpene glycosides, named Capsiansides, were obtained from the part of the polar ingredients in the fresh fruits of Capsicum plants, C.annuum L. var. fasciculatum Irish, C.annuum L. var. conoides Bailey, and C.annuum L. var. grossum Their structures were disclosed mainly by the spectroscopic means (^1H-^1H, ^1H-^<13>C and ^1H-^<13>C long range COSY and NOE NMR experiments). They are classified into two groups, the glycosides (Capsiansides I-V) of the geranyl-linalool derivatives and the ones (Capsiansides A-E) having two acyclic diterpene moieties in the respective molecule. These acyclic diterpenes occur rarely in nature. Capsiansides C and D of them were shown to have inhibitory activity for angiotensin converting enzyme. We have plans to perform various pharmacological tests and to practice cyclization with regard to these compounds by the aid of catalytic acid or enzyme.