鉄と鋼
Online ISSN : 1883-2954
Print ISSN : 0021-1575
ISSN-L : 0021-1575
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有機酸錯体中の鉄(II)イオンの酸化状態の安定性
打越 雅仁 鈴木 茂
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2025 年 111 巻 2 号 p. 58-62

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Oral iron medications, a treatment for iron deficiency anemia, frequently cause side effects such as nausea, vomiting, and diarrhea. The mechanism of toxicity has not been elucidated, and therefore measures to reduce toxicity have not been established. The influence of the oxidation state of iron is considered as one of the factors that may cause side effects, so the oxidation state of iron was confirmed using ultraviolet-visible absorption spectroscopy when oral iron medications dissolve in the stomach. The main components of oral iron medications are inorganic and organic acid iron complexes, with citric acid, fumaric acid, sulfuric acid, etc. used as ligands. The influence of the valence of the ligand on the stability of the oxidation state of iron was also examined.

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© 2025 一般社団法人 日本鉄鋼協会

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