Trends in Glycoscience and Glycotechnology
Online ISSN : 1883-2113
Print ISSN : 0915-7352
ISSN-L : 0915-7352
Article for JSCR 40th Anniversary Issue
Lipid Rafts Heterogeneity
Kohji Kasahara
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2019 Volume 31 Issue 181 Pages SE23-SE24

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Abstract

Lipid rafts, glycosphingolipid microdomains, are compositionally and functionally heterogenous in the cell membrane. Recent reports have demonstrated that lipid rafts are spatially heterogeneous in the single cell membrane. In central nervous system, ganglioside GD3 rafts are involved in migration of granule cells during the early stage of development. In blood coagulation system, clot retraction is mediated by fibrin- integrin αIIbβ3-myosin axis in platelet sphingomyelin rafts.

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© 2019 FCCA (Forum: Carbohydrates Coming of Age)
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